Description

18-Dehydroxycytochalasin H is a specialized cytochalasin derivative, a class of fungal metabolites known for their potent biological activity. This compound serves as a valuable biochemical tool and reference standard for research into cytoskeletal dynamics and cellular processes. It is primarily utilized by researchers and developers in the life sciences sector, particularly in pharmacology, cell biology, and molecular biology for mechanistic studies and assay development.

Application

• Biochemical Research: Used as a reference standard and tool compound in studies investigating actin filament disruption and cytoskeleton function.
• Pharmacological Studies: Employed in the research and development of novel therapeutic agents targeting cellular motility and morphology.
• Cell Biology: Applied in vitro to study cell division, migration, and shape changes in various cell lines.
• Molecular Probe Development: Serves as a key intermediate or active component in the synthesis of probes for imaging and diagnostic applications.
• Academic Research: Utilized in university and institutional laboratories for fundamental research on natural product bioactivity.

Basic Information

Product Name	18-Dehydroxycytochalasin H
CAS No.	141994-72-1
Molecular Formula	C29H37NO5
Molecular Weight	479.61 g/mol
Synonyms	18-Dehydroxycytochalasin H; 6,7-Epoxy-18-dehydroxycytochalasin H; [1S-(1α,6β,7β,10α,12α,13α,14α,16E,18E)]-6,7-Epoxy-23,24-dinorcholesta-2,16,18-trien-4-one, 1,13,14,22-tetrahydroxy-10-methyl-; Cytochalasin H derivative
EINECS	Contact for details

Quality Control

Our 18-Dehydroxycytochalasin H is produced under stringent quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals to guarantee product integrity and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.