Description

Bq-610 CAS NO 141595-53-1 is a high-purity, non-peptide endothelin receptor antagonist used in advanced biochemical and pharmacological research. This compound is critical for studying the role of endothelin in cardiovascular regulation, pulmonary hypertension, and related disease pathways. It is an essential tool for pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) focused on developing novel therapeutics.

Application

• Pharmacological Research: Primary tool for selective antagonism of endothelin ETA receptors in in vitro and in vivo studies.
• Cardiovascular Disease Models: Used to investigate mechanisms in hypertension, heart failure, and atherosclerosis.
• Pulmonary Research: Applied in studies of pulmonary arterial hypertension (PAH) and related vascular remodeling.
• Signal Transduction Studies: Elucidates endothelin-mediated cellular signaling pathways and second messenger systems.
• Drug Discovery & Development: Serves as a reference standard and lead compound in screening assays for new endothelin receptor antagonists.
• Academic & Institutional Research: Supports basic science investigations into the physiological and pathological roles of endothelin.

Basic Information

Product Name	Bq-610
CAS No.	141595-53-1
Molecular Formula	C29H38N4O6
Molecular Weight	538.64 g/mol
Synonyms	BQ-610; BQ 610; Cyclo(D-α-aspartyl-3-[(4-phenylpiperazin-1-yl)carbonyl]-L-alanyl-L-α-aspartyl-D-2-(2-thienyl)glycyl-L-leucyl-D-tryptophyl)disulfide; N-[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-2-[[(2R)-2-[[(2S)-1-Hydroxy-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamoyl]-2-(thiophen-2-yl)ethyl]carbamoyl]-3-carboxypropyl]carbamoyl]ethyl]carbamoyl]-3-carboxypropyl]carbamoyl]-1-(4-phenylpiperazine-1-carbonyl)ethyl]β-alanine
EINECS	Contact for details

Quality Control

Every batch of Bq-610 is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) that detail identity, purity, and impurity profiles, ensuring compliance with research-grade standards. Our quality commitment supports reproducible and reliable results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.