Description

1-Chloro-5-Isoquinolinesulfonyl Chloride is a versatile and highly reactive bifunctional heterocyclic building block. This compound is valued for its role as a key sulfonylation reagent and intermediate in sophisticated organic synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active molecules targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its reactive sites to create novel active ingredients.
• Chemical Biology Probe Synthesis: Employed to create sulfonamide-based probes for studying enzyme function and protein-protein interactions within biological systems.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers with specific functional properties.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services, enabling the production of complex, tailor-made compounds for clients.

Basic Information

Product Name	1-Chloro-5-Isoquinolinesulfonyl Chloride
CAS No.	141519-77-9
Molecular Formula	C9H5Cl2NO2S
Molecular Weight	262.11 g/mol
Synonyms	5-Chloro-1-Isoquinolinesulfonyl Chloride; 1-Chloroisoquinoline-5-sulfonyl Chloride; Isoquinoline-5-sulfonyl Chloride, 1-chloro-; 1-Chloro-5-sulfochloridoisoquinoline; 141519-77-9; 1-Chloro-5-(chlorosulfonyl)isoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloro-5-Isoquinolinesulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.