Description

n-Butyl-1-Deoxygalactonojirimycin is a potent and selective glycosidase inhibitor, specifically targeting α-galactosidase enzymes. This compound is a critical research tool and pharmaceutical intermediate for investigating and developing treatments for lysosomal storage disorders, such as Fabry disease. It is primarily utilized by researchers in pharmaceutical development, academic biochemistry, and biotechnology for enzyme inhibition studies and as a lead compound in therapeutic agent synthesis.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of pharmacological chaperone drugs for lysosomal storage diseases.
• Enzyme Inhibition Studies: Used as a specific and potent inhibitor of α-galactosidase in biochemical and enzymatic assays to study enzyme function and mechanism.
• Glycobiology Research: A vital tool for investigating glycosphingolipid metabolism and the role of glycosidases in cellular processes.
• Preclinical Development: Employed in animal model studies to evaluate the efficacy of potential therapies for Fabry disease and related disorders.
• Reference Standard: Used as a high-purity analytical standard in quality control and method development for related pharmaceutical compounds.

Basic Information

Product Name	n-Butyl-1-Deoxygalactonojirimycin
CAS No.	141206-42-0
Molecular Formula	C14H27NO5
Molecular Weight	289.37 g/mol
Synonyms	1-Deoxygalactonojirimycin N-Butyl Derivative; NB-DGJ; N-Butyl-deoxygalactonojirimycin; (2R,3R,4R,5S)-2-(Butylamino)methyl-3,4,5-trihydroxypiperidine; AT1001; Migalastat Impurity; Fabry Disease Chaperone Intermediate; α-Galactosidase Inhibitor
EINECS	Contact for details

Quality Control

Our n-Butyl-1-Deoxygalactonojirimycin is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant GMP guidelines for advanced pharmaceutical intermediates to support our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.