Description

4-Bromo-Toluene-3-Sulfonyl Chloride is a versatile and highly reactive organosulfur compound used as a key sulfonylation reagent and building block in advanced organic synthesis. Its primary value lies in introducing the sulfonyl chloride functional group, enabling the creation of sulfonamides and sulfonate esters critical for developing active pharmaceutical ingredients and specialty chemicals. This intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require high-purity, reliable synthetic building blocks.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides where the sulfonyl moiety imparts specific biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Derivatization: Employed in analytical chemistry to derivative compounds for detection or separation via HPLC or LC-MS.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex sulfonated dyes and colorants.
• Ligand Synthesis for Catalysis: Used to prepare specialized sulfonated ligands for metal complexes in catalytic applications.

Basic Information

Product Name	4-Bromo-Toluene-3-Sulfonyl Chloride
CAS No.	141113-98-6
Molecular Formula	C7H6BrClO2S
Molecular Weight	269.54 g/mol
Synonyms	3-Bromo-4-methylbenzenesulfonyl chloride; 4-Methyl-3-bromobenzenesulfonyl chloride; 3-Bromo-p-toluenesulfonyl chloride; 4-Bromo-3-methylbenzenesulfonyl chloride; 3-Bromo-4-toluenesulfonyl chloride; 4-Bromotoluene-3-sulfonyl chloride; 1-Bromo-2-methyl-5-(chlorosulfonyl)benzene; Toluene-4-bromo-3-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-Toluene-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.