Description

Matlystatin D is a potent and selective inhibitor of matrix metalloproteinases (MMPs), a class of enzymes critical in tissue remodeling and disease progression. This compound is valued in research for its ability to modulate extracellular matrix degradation, providing a key tool for studying cancer metastasis, arthritis, and other inflammatory conditions. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in drug discovery and biochemical pathway analysis.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the role of MMPs in tumor invasion, angiogenesis, and metastasis.
• Drug Discovery & Development: Serves as a lead compound or pharmacological tool for screening and developing novel therapeutic agents targeting MMP-related diseases.
• Enzymology Studies: Employed in biochemical assays to determine enzyme kinetics, inhibition constants (Ki/IC50), and specificity profiles of various MMP isoforms.
• Inflammatory Disease Models: Applied in preclinical research for conditions like rheumatoid arthritis, atherosclerosis, and periodontal disease where MMP activity is dysregulated.
• Academic & Contract Research: Supplied to universities and CROs for fundamental research into cell migration, tissue repair, and protease biology.

Basic Information

Product Name	Matlystatin D
CAS No.	140638-25-1
Molecular Formula	C30H48N4O7
Molecular Weight	576.73 g/mol
Synonyms	Matlystatin D; FR 901277; MMP Inhibitor FR901277; (2S)-2-[[(2S,3R)-3-[[(2S)-2-[[(2S,3S)-3-[[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-2-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoic acid
EINECS	Contact for details

Quality Control

Our Matlystatin D is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade standards. We support cGMP practices for advanced pharmaceutical development needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation. Store in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.