Description

1-Fluoro-2,6-Dichloropyridinium Tetrafluoroborate is a high-purity, reactive fluorination and halogenation reagent used in advanced organic synthesis. Its primary value lies in its ability to introduce fluorine atoms or activate specific sites in complex molecules, enabling the creation of novel compounds with tailored properties. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where precise molecular modification is critical for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the selective fluorination of active pharmaceutical ingredients (APIs) and complex heterocycles.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides where fluorine substitution enhances biological activity and stability.
• Material Science Research: Facilitates the synthesis of fluorinated organic semiconductors, liquid crystals, and polymers with unique electronic and surface properties.
• Fluorination Reactions: Acts as a source of electrophilic fluorine for the preparation of aryl and heteroaryl fluorides under mild conditions.
• Chlorination & Activation: Serves as a chlorinating agent and a precursor for generating other reactive pyridinium species in situ.
• Cross-Coupling Precursor: Provides a versatile halogenated pyridine scaffold for subsequent metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille).
• Labeling & Tracer Chemistry: Useful in the preparation of 18F-labeled compounds for Positron Emission Tomography (PET) imaging research.

Basic Information

Product Name	1-Fluoro-2,6-Dichloropyridinium Tetrafluoroborate
CAS No.	140623-89-8
Molecular Formula	C5H2Cl2F5BN
Molecular Weight	273.79 g/mol
Synonyms	2,6-Dichloro-1-fluoropyridinium Tetrafluoroborate; 1-Fluoro-2,6-dichloropyridin-1-ium Tetrafluoroborate; 2,6-Dichloro-1-fluoropyridin-1-ium Tetrafluoroborate; F-DCP; Fluorodichloropyridinium Tetrafluoroborate; Electrophilic Fluorinating Reagent; Fluorination Reagent; 1-Fluoro-2,6-dichloropyridinium BF4
EINECS	Contact for details

Quality Control

Our 1-Fluoro-2,6-Dichloropyridinium Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and ion chromatography, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
BF4- Content (IC)	28.0 - 32.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.