Description

2,3,6-Tri-o-Octyl-α-Cyclodextrin is a chemically modified derivative of α-cyclodextrin, where three primary hydroxyl groups are per-octylated, significantly enhancing its lipophilicity and molecular encapsulation capabilities. This modification is crucial for forming stable inclusion complexes with a wide range of hydrophobic guest molecules in aqueous and non-aqueous media. It is an essential advanced material for researchers and formulators in the pharmaceutical, agrochemical, and specialty chemical industries seeking to improve solubility, stability, and bioavailability of active compounds.

Application

• Pharmaceutical Research & Formulation: Used as a solubility enhancer and stabilizer for poorly water-soluble drug candidates in pre-formulation studies and novel drug delivery systems.
• Catalysis & Chemical Synthesis: Acts as a phase-transfer catalyst or a supramolecular host in organic synthesis to facilitate reactions and control selectivity.
• Analytical Chemistry: Employed in chiral separation techniques, such as in capillary electrophoresis or as a stationary phase modifier in chromatography, for enantiomer resolution.
• Agrochemical Formulations: Enhances the solubility and efficacy of hydrophobic pesticides and herbicides, improving their environmental delivery and performance.
• Fragrance & Flavor Stabilization: Encapsulates volatile or sensitive aroma compounds to control release and prolong shelf-life in consumer products.
• Material Science: Serves as a building block for creating functionalized surfaces, polymers, and sensors with specific molecular recognition properties.

Basic Information

Product Name	2,3,6-Tri-o-Octyl-α-Cyclodextrin
CAS No.	140395-31-9
Molecular Formula	C96H176O30
Molecular Weight	~1858.37 g/mol
Synonyms	2,3,6-Tri-O-octyl-α-cyclodextrin; α-Cyclodextrin, 2,3,6-tri-O-octyl-; Octylated α-cyclodextrin; Trioctyl-α-cyclodextrin; 2,3,6-Tri-O-octyl-α-CD; Hydrophobic α-cyclodextrin derivative; Per(2,3,6-tri-O-octyl)-α-cyclodextrin; TOO-α-CD
EINECS	Contact for details

Quality Control

Our 2,3,6-Tri-o-Octyl-α-Cyclodextrin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including NMR and HPLC, to confirm structure, substitution degree, and purity. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Degree of Substitution (NMR)	~3.0 (Trioctyl per cyclodextrin ring)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.