Description

6-Iodoclorgyline is a halogenated derivative of the well-characterized monoamine oxidase inhibitor clorgyline. This compound is a crucial high-purity biochemical tool and a versatile synthetic intermediate for advanced research and development. It is primarily utilized by pharmaceutical researchers and contract development and manufacturing organizations (CDMOs) engaged in neuroscience, medicinal chemistry, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Biochemical Research: Used as a key reference standard and probe in neuroscience studies targeting monoamine oxidase (MAO) enzymes.
• Medicinal Chemistry: Serves as a sophisticated building block for the synthesis of novel MAO inhibitors and other pharmacologically active compounds.
• Pharmaceutical Intermediate: Employed in the research-scale development and production of potential therapeutic agents.
• Academic Research: Facilitates studies in neurochemistry, enzyme kinetics, and structure-activity relationship (SAR) analysis.
• Contract Manufacturing: Supplied to CDMOs for custom synthesis projects requiring high-purity, specialized intermediates.
• Reference Standard: Acts as a certified material for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	6-Iodoclorgyline
CAS No.	140163-68-4
Molecular Formula	C13H12ClIN2
Molecular Weight	358.61 g/mol
Synonyms	6-Iodo-clorgyline; N-Methyl-N-(2-propynyl)-1-(6-iodobenzofuran-5-yl)methylamine; 1-[(6-Iodo-1-benzofuran-5-yl)methyl]-N-methylprop-2-yn-1-amine; 6-Iodo Clorgyline; 6-Iodoclorgilin; 6-I-Clorgyline
EINECS	Contact for details

Quality Control

Our 6-Iodoclorgyline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS). A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.