Description

2-Propenenitrile,2-Fluoro-3-(2-Pyridinyl)-,(E)-(9Ci) is a specialized fluorinated pyridine derivative and a key building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates both a nitrile and a fluorine atom adjacent to a pyridine ring, enabling precise chemical modifications. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and fluorinated bioactive molecules.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and advanced materials with specific electronic or surface properties.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions, cycloadditions, and other advanced organic transformations to construct complex heterocyclic systems.
• Ligand Synthesis: Useful for preparing novel pyridine-based ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: Acts as a model compound in academic and industrial research exploring the reactivity of vinyl fluorides and fluorinated nitriles.

Basic Information

Product Name	2-Propenenitrile,2-Fluoro-3-(2-Pyridinyl)-,(E)-(9Ci)
CAS No.	140137-15-1
Molecular Formula	C9H5FN2
Molecular Weight	160.15 g/mol
Synonyms	(E)-2-Fluoro-3-(pyridin-2-yl)acrylonitrile; (E)-2-Fluoro-3-(2-pyridinyl)-2-propenenitrile; 2-Fluoro-3-(2-pyridinyl)-2-propenenitrile, (E)-; trans-2-Fluoro-3-(2-pyridyl)acrylonitrile; 140137-15-1; (E)-β-Fluoro-2-pyridineacrylonitrile; (E)-2-Fluoro-3-(2-pyridyl)acrylonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Propenenitrile,2-Fluoro-3-(2-Pyridinyl)-,(E)-(9Ci) is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (E/Z Ratio)	≥ 98:2 (E/Z)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.