Description

Cyclopropanesulfonyl Chloride is a versatile and highly reactive organosulfur compound primarily used as a key sulfonylation reagent and building block in advanced organic synthesis. Its unique cyclopropyl ring structure imparts distinct steric and electronic properties, making it valuable for creating novel molecular architectures with specific biological or material characteristics. This intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries engaged in developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the cyclopropane moiety enhances biological activity.
• Material Science Research: Serves as a precursor for functionalized polymers and advanced materials with tailored surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in metal-catalyzed cross-coupling reactions to form carbon-sulfur bonds.
• Sulfonylation Agent: Used to introduce the sulfonyl chloride functional group into target molecules under controlled conditions.

Basic Information

Product Name	Cyclopropanesulfonyl Chloride
CAS No.	139631-62-2
Molecular Formula	C3H5ClO2S
Molecular Weight	140.59 g/mol
Synonyms	Cyclopropanesulfonyl chloride; Cyclopropanesulfonic acid chloride; Cyclopropylsulfonyl chloride; Cyclopropane-1-sulfonyl chloride; 1-Cyclopropanesulfonyl chloride; Cyclopropanesulphonic acid chloride; Cyclopropanesulphonyl chloride; Cyclopropanesulfonylchloride
EINECS	Contact for details

Quality Control

Our Cyclopropanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.