Description

Pimilprost (Jan) CAS NO 139403-31-9 is a high-purity synthetic prostaglandin analog, a critical active pharmaceutical ingredient (API) used in advanced ophthalmic formulations. Its primary value lies in its potent and selective pharmacological activity for managing intraocular pressure. This compound is essential for pharmaceutical manufacturers and research institutions developing next-generation treatments for glaucoma and ocular hypertension. We supply it under strict quality control to ensure batch-to-batch consistency for your formulation needs.

Application

• Ophthalmic Drug Manufacturing: As the key active pharmaceutical ingredient (API) in prescription eye drop formulations for glaucoma.
• Pharmaceutical R&D: For preclinical and clinical studies investigating new prostaglandin-based therapies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical labs.
• Formulation Development: Used in the development of novel drug delivery systems, such as sustained-release implants or gels.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of finished dosage forms.
• Academic Research: Utilized in biochemical and pharmacological research to study prostaglandin receptor mechanisms.

Basic Information

Product Name	Pimilprost (Jan)
CAS No.	139403-31-9
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	Pimilprost; 9-Oxo-11α,15α-dihydroxy-17-phenyl-18,19,20-trinorprosta-5Z,13E-dien-1-oic acid; AL-12182; UNII-9H8L7686XG; Isopropyl (Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-3-hydroxy-4-(3-methoxyphenoxy)-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoate; Prostaglandin F2α analog; Antiglaucoma Prostaglandin
EINECS	Contact for details

Quality Control

Our Pimilprost is manufactured and tested to meet exacting standards for pharmaceutical actives. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality system ensures compliance with ICH Q7 guidelines and relevant pharmacopeial standards. Certificates of Analysis (COA) are available upon request to support your regulatory filings and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccated environment after opening to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.