Description

Actin Polymerization Inhibitor 25 Kda CAS NO 139247-56-6 is a high-purity, cell-permeable peptide designed to specifically and potently inhibit actin polymerization. This compound is a critical research tool for disrupting the actin cytoskeleton, enabling the study of cellular processes such as motility, division, and intracellular transport. It is essential for life science researchers, pharmaceutical developers, and diagnostic manufacturers working in cell biology, neurobiology, and cancer research.

Application

• Cytoskeleton Research: Fundamental studies on actin filament dynamics, polymerization kinetics, and cytoskeletal architecture.
• Cell Biology & Signaling: Investigation of cellular processes dependent on actin remodeling, including cell migration, adhesion, and phagocytosis.
• Neuroscience Research: Exploration of synaptic plasticity, dendritic spine morphology, and neuronal growth cone guidance.
• Cancer & Metastasis Studies: Research into the role of actin in tumor cell invasion, metastasis, and drug resistance mechanisms.
• Drug Discovery & Screening: Used as a reference inhibitor in high-throughput assays to identify novel compounds targeting the actin cytoskeleton.
• Diagnostic Development: A key reagent in developing assays for diseases involving cytoskeletal abnormalities.

Basic Information

Product Name	Actin Polymerization Inhibitor 25 Kda
CAS No.	139247-56-6
Molecular Formula	Contact for details
Molecular Weight	~25000 Da (25 KDa)
Synonyms	Actin Inhibitor II; Latrunculin A (Note: Latrunculin A is a potent natural actin polymerization inhibitor, this product may be a related synthetic peptide or derivative); Cytochalasin D (alternative actin inhibitor class); Actin Depolymerizing Agent; Cytoskeleton Disrupting Peptide; Cell-Permeable Actin Inhibitor; 25 kDa Actin Polymerization Blocker
EINECS	Contact for details

Quality Control

Our Actin Polymerization Inhibitor 25 Kda is produced under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by HPLC, mass spectrometry for molecular weight confirmation, and functional activity testing in cell-based assays. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Aliquot to avoid repeated freeze-thaw cycles. Handle under inert conditions where applicable to maintain peptide integrity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Complies
Purity (HPLC)	≥ 95%
Molecular Weight (MS)	24,500 - 25,500 Da
Biological Activity (Cell-based assay)	≥ 90% inhibition at specified concentration
Endotoxin Level	< 1.0 EU/mg
Solubility	Soluble in DMSO or specified buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.