Description

11-Deoxyprostaglandin E2-1-Alcohol is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of more complex prostaglandin derivatives, which are critical for studying and modulating biological pathways related to inflammation, pain, and cellular regulation. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing novel therapeutic agents and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel prostaglandin-based drug candidates.
• Biochemical Research: Used as a reference standard or probe in studies investigating eicosanoid signaling pathways, receptor binding, and enzyme activity.
• Metabolite Synthesis: Employed in the preparation of specific prostaglandin metabolites for analytical and pharmacological testing.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of target compounds.
• Process Development: Acts as a key intermediate in scaling up production processes for prostaglandin APIs under GMP conditions.

Basic Information

Product Name	11-Deoxyprostaglandin E2-1-Alcohol
CAS No.	138898-70-1
Molecular Formula	C₂₀H₃₄O₄
Molecular Weight	338.48 g/mol
Synonyms	11-Deoxy-PGE2-1-ol; (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-ol; 11-Deoxyprostaglandin E2 alcohol; Prosta-5,13-dien-1-ol, 9,11,15-trihydroxy-, (5Z,9S,11R,13E,15S)-; PGE2-1-ol, 11-deoxy-
EINECS	Contact for details

Quality Control

Every batch of 11-Deoxyprostaglandin E2-1-Alcohol is manufactured and tested to meet stringent quality standards suitable for research and pharmaceutical intermediate use. Our products undergo rigorous quality testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC, to ensure consistency and reliability. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below to minimize oxidation and ensure long-term stability. The container should be kept in a dry, cool, and well-ventilated area. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.