Description

5-Bromo-1,2,3-Trifluorobenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring fluorinated aromatic cores to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethylbenzene moiety is a common pharmacophore.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where fluorine atoms improve thermal stability and electronic properties.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form biaryl structures.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands for catalysis, and advanced organic frameworks.

Basic Information

Product Name	5-Bromo-1,2,3-Trifluorobenzene
CAS No.	138526-69-9
Molecular Formula	C6H2BrF3
Molecular Weight	210.98 g/mol
Synonyms	1-Bromo-3,4,5-trifluorobenzene; 3,4,5-Trifluorobromobenzene; Benzene, 5-bromo-1,2,3-trifluoro-; 5-Bromo-1,2,3-trifluorobenzol; 138526-69-9 (CAS); 5-Br-1,2,3-F3-C6H2
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,2,3-Trifluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.