Description

m-Erythro-Chloramphenicol CAS NO 138125-71-0 is a specific stereoisomer of the broad-spectrum antibiotic chloramphenicol, distinguished by its unique spatial configuration at the molecular level. This precise stereochemistry is critical for researchers and developers in the pharmaceutical industry who require defined compounds for advanced studies and synthesis. It is primarily utilized in analytical research, as a reference standard for quality control, and as a key intermediate in the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of chloramphenicol and related compounds in analytical methods like HPLC and LC-MS.
• Biochemical Research: Serves as a critical tool in microbiological and pharmacological studies to investigate antibiotic mechanisms of action, resistance, and stereochemical effects.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the controlled synthesis of specialized antibiotic formulations where the specific m-erythro configuration is required.
• Quality Control & Method Development: Essential for calibrating instruments and validating analytical procedures in pharmaceutical QC laboratories to ensure regulatory compliance.

Basic Information

Product Name	m-Erythro-Chloramphenicol
CAS No.	138125-71-0
Molecular Formula	C11H12Cl2N2O5
Molecular Weight	323.13 g/mol
Synonyms	Chloramphenicol m-erythro isomer; (1R,2R)-2,2-Dichloro-N-[1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide; D-threo-1-(p-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol (m-erythro form); Antibiotic m-erythro isomer; Chloromycetin m-erythro form
EINECS	Contact for details

Quality Control

Our m-Erythro-Chloramphenicol is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant pharmacopeial standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Specific Rotation	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.