Description

Ng-Monomethyl-D-Arginine Monoacetate is a high-purity, chemically modified derivative of D-Arginine, specifically methylated at the guanidino nitrogen. This compound serves as a critical research-grade biochemical and a key chiral building block in advanced pharmaceutical synthesis. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research institutions for investigating nitric oxide synthase (NOS) inhibition and developing novel peptide-based therapeutics.

Application

• Nitric Oxide Synthase (NOS) Research: As a selective inhibitor for studying the role of nitric oxide in various physiological and pathological processes.
• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of peptide drugs and enzyme inhibitors targeting cardiovascular and neurological diseases.
• Biochemical Standard: Used as a reference standard in analytical methods (HPLC, MS) for quality control and metabolic studies.
• Proteomics & Cell Signaling Studies: Employed in research to modulate arginine-dependent pathways and understand post-translational methylation effects.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block in the preparation of enantiomerically pure compounds.

Basic Information

Product Name	Ng-Monomethyl-D-Arginine Monoacetate
CAS No.	137694-75-8
Molecular Formula	C9H19N5O3 • C2H4O2
Molecular Weight	305.33 g/mol
Synonyms	D-NG-Monomethylarginine acetate; (R)-2-Amino-5-[(methylamino)iminomethyl]aminopentanoic acid monoacetate; Nω-Methyl-D-arginine acetate salt; L-NMMA (D-isomer) acetate; D-Arg(NG-Me) acetate; ADMA (D-isomer) acetate; NG-Monomethyl-D-arginine acetate; H-D-Arg(Me)-OH • AcOH
EINECS	Contact for details

Quality Control

Our Ng-Monomethyl-D-Arginine Monoacetate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm the D-configuration, and residual solvent testing. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.