Description

Ng-Monomethyl-D-Arginine Monoacetate is a high-purity, chemically modified derivative of D-Arginine, specifically methylated at the guanidino nitrogen. This compound is a critical biochemical tool and pharmaceutical intermediate, valued for its role as a selective inhibitor of nitric oxide synthase (NOS). It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science research sectors who require precise and reliable building blocks for drug discovery and development.

Application

• Nitric Oxide Synthase (NOS) Research: Primarily used as a potent and selective inhibitor of neuronal NOS (nNOS) in biochemical and pharmacological studies to investigate the role of nitric oxide in various physiological and pathological processes.
• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel therapeutic agents targeting cardiovascular, neurological, and inflammatory diseases.
• Biochemical Reagent: Employed in enzyme kinetics studies, cell culture experiments, and as a standard reference material in analytical method development for NOS-related assays.
• Academic & Contract Research: Utilized by universities, research institutes, and CROs (Contract Research Organizations) for fundamental scientific research and preclinical drug development programs.

Basic Information

Product Name	Ng-Monomethyl-D-Arginine Monoacetate
CAS No.	137694-74-7
Molecular Formula	C9H19N5O2 • C2H4O2
Molecular Weight	305.33 g/mol
Synonyms	D-NMMA; D-NG-Monomethylarginine acetate; (R)-2-Amino-5-[(methylamino)iminomethyl]aminopentanoic acid monoacetate; Nω-Methyl-D-arginine acetate; L-NMMA (D-isomer); Nitric Oxide Synthase Inhibitor (D-form); D-Arg(NO2)-OMe • AcOH; N-Methyl-D-arginine acetate salt
EINECS	Contact for details

Quality Control

Our Ng-Monomethyl-D-Arginine Monoacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.