Description

Zaragozic Acid C is a potent, naturally occurring inhibitor of squalene synthase, a key enzyme in the sterol biosynthesis pathway. This compound is of significant interest for its role as a biochemical tool in metabolic research and its potential in therapeutic development. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for studying cholesterol metabolism and exploring novel lipid-lowering agents.

Application

• Biochemical Research: A critical tool compound for studying the regulation of the mevalonate pathway and sterol biosynthesis in vitro and in vivo.
• Pharmaceutical R&D: Serves as a lead compound or reference standard in the discovery and development of novel cholesterol-lowering drugs and antifungal agents.
• Enzyme Inhibition Studies: Used to specifically inhibit squalene synthase activity to investigate downstream biological effects and validate drug targets.
• Metabolic Pathway Analysis: Employed in cell-based assays and animal models to elucidate the role of isoprenoid and sterol synthesis in various disease states.
• Academic Research: Utilized in university and institutional labs for fundamental research in biochemistry, cell biology, and pharmacology.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Zaragozic Acid C
CAS No.	137681-56-2
Molecular Formula	C₄₄H₆₈O₁₄
Molecular Weight	845.0 g/mol
Synonyms	Zaragozic Acid C; Squalestatin 1; Zaragozic Acid A1; Squalestatin S1; L-731,120; (2R,3S,4S,5R,6S)-5,6-Dihydroxy-2-[[(2S,3R,4S,5S,6R)-5-hydroxy-3,4,6-tris[[(1S,2S,6S,8S)-2,6,8-trimethyl-1-[(2S)-1-oxo-3-phenyl-2-propenyl]oxy]bicyclo[4.2.0]oct-4-yl]oxy-2-tetrahydro-2H-pyran-2-yl]methoxy]-3,4-pyridinedicarboxylic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our Zaragozic Acid C is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.