Description

Ryanodyl 3-(Pyridine-3-Carboxylate) is a specialized chemical compound belonging to the class of ryanodine receptor modulators. This compound is of significant interest for its role in calcium channel research and its potential as a key intermediate in advanced pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in neurobiological studies, cardiac research, and the synthesis of novel therapeutic agents targeting intracellular calcium signaling pathways.

Application

• Research Chemical: A critical tool for studying ryanodine receptor (RyR) function and calcium-induced calcium release (CICR) mechanisms in cellular physiology.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates targeting cardiovascular and neurological disorders.
• Biochemical Assay Development: Used in the development and validation of high-throughput screening assays for drug discovery programs focused on calcium channel modulators.
• Academic Research: Employed in university and institutional labs for fundamental research in muscle contraction, neuronal signaling, and apoptosis.
• Reference Standard: Provides a qualified standard for analytical method development and quality control in related API manufacturing.

Basic Information

Product Name	Ryanodyl 3-(Pyridine-3-Carboxylate)
CAS No.	137441-82-8
Molecular Formula	C13H12N2O3
Molecular Weight	244.25 g/mol
Synonyms	3-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-1-methyl-2-oxo-5-(phenylmethyl)-, methyl ester; Ryanodine derivative; Ryanodyl ester; 1-Methyl-2-oxo-5-benzyl-1,2,3,6-tetrahydropyridine-3-carboxylic acid methyl ester; 5-Benzyl-1-methyl-2-oxo-1,2,3,6-tetrahydropyridine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Ryanodyl 3-(Pyridine-3-Carboxylate) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.