Description

N(4)-(Guanosin-7-Yl)-4-Aminoquinoline 1-Oxide is a specialized nucleoside-quinoline hybrid compound of significant interest in advanced biochemical research. This molecule is valued for its unique structure, which combines the nucleobase guanine with a quinoline moiety, creating a versatile scaffold for probing nucleic acid interactions and modifications. It serves as a critical intermediate and reference standard for researchers in pharmaceutical development, chemical biology, and oncological studies, particularly those investigating DNA adduct formation and targeted therapeutic agents.

Application

• Biochemical Research Standard: Used as a high-purity reference material in studies of nucleoside modification and DNA damage mechanisms.
• Pharmaceutical Intermediate: Serves as a key synthetic building block in the development of novel anticancer and antiviral drug candidates.
• Chemical Biology Probe: Employed to investigate specific interactions between modified nucleosides and biological targets, such as enzymes and receptors.
• Oncological Studies: Utilized in research focused on the role of specific DNA adducts in mutagenesis and carcinogenesis pathways.
• Academic & Institutional Research: A vital tool for universities and research institutes conducting fundamental studies in organic synthesis and medicinal chemistry.

Basic Information

Item	Details
Product Name	N(4)-(Guanosin-7-Yl)-4-Aminoquinoline 1-Oxide
CAS No.	137339-24-3
Molecular Formula	C19H19N7O6
Molecular Weight	441.40 g/mol
Synonyms	7-(4-Aminoquinolin-1-ium-1-yl)guanosine 1-Oxide; N4-(Guanosin-7-yl)-4-aminoquinoline 1-Oxide; 4-Aminoquinoline-1-oxide-guanosine adduct; G-C8-4-AQO; Guanine-Quinoline Conjugate; 1-Oxide-4-aminoquinoline-Guanosine Derivative; Research Compound 137339-24-3
EINECS	Contact for details

Quality Control

Our N(4)-(Guanosin-7-Yl)-4-Aminoquinoline 1-Oxide is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the exacting standards required for research applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.