Description

5-Bromo-2,3,6-Trifluorobenzaldehyde is a versatile fluorinated aromatic aldehyde building block, distinguished by its unique substitution pattern of bromine and fluorine atoms. This compound is valued for its high reactivity, particularly in cross-coupling reactions and as a precursor for synthesizing complex heterocyclic and pharmaceutical intermediates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to create novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl or difluoromethyl ether groups.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form biaryl structures.
• Fluorinated Liquid Crystal Research: Acts as a core component in the synthesis of fluorinated liquid crystals for display technologies.

Basic Information

Product Name	5-Bromo-2,3,6-Trifluorobenzaldehyde
CAS No.	137234-99-2
Molecular Formula	C7H2BrF3O
Molecular Weight	244.99 g/mol
Synonyms	2,3,6-Trifluoro-5-bromobenzaldehyde; 5-Bromo-2,3,6-trifluorobenzenecarboxaldehyde; Benzaldehyde, 5-bromo-2,3,6-trifluoro-; 137234-99-2; 5-Bromo-2,3,6-trifluoro benzaldehyde; 5-Br-2,3,6-F3-benzaldehyde
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3,6-Trifluorobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in regulated research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.