Description

n-Methyl-4-(Trifluoromethyl)-Benzeneethanamine is a versatile fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the reactive amine functionality, enabling precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for CNS-active molecules and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and advanced organic electronic materials.
• Fluorine Chemistry Building Block: Essential for introducing the pharmacologically beneficial trifluoromethyl moiety into complex molecular architectures.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	n-Methyl-4-(Trifluoromethyl)-Benzeneethanamine
CAS No.	137069-25-1
Molecular Formula	C10H12F3N
Molecular Weight	203.20 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-N-methylethanamine; 2-[4-(Trifluoromethyl)phenyl]-N-methylethanamine; 4-(Trifluoromethyl)phenethylmethylamine; N-Methyl-4-(trifluoromethyl)phenethylamine; N-Methyl-2-[4-(trifluoromethyl)phenyl]ethanamine; α-Methyl-4-(trifluoromethyl)phenethylamine; 1-(4-Trifluoromethylphenyl)-2-(methylamino)ethane
EINECS	Contact for details

Quality Control

Our n-Methyl-4-(Trifluoromethyl)-Benzeneethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.