Description

7-Oxabicyclo[4.1.0]heptane, 3-(fluoromethyl)- is a specialized fluorinated oxirane derivative, a high-value building block in advanced organic synthesis. Its unique strained bicyclic structure and reactive epoxide ring make it a critical intermediate for introducing fluoromethylated motifs into complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of fluorinated drug candidates, particularly in CNS and oncology research.
• Agrochemical Synthesis: Used to create novel fluorinated pesticides and herbicides with enhanced biological activity and stability.
• Material Science: Building block for specialty polymers and advanced materials requiring fluorinated components for specific surface properties.
• Ligand & Catalyst Development: Precursor for creating chiral, fluorinated ligands used in asymmetric catalysis.
• Fluorine Chemistry Research: A valuable tool for studying ring-opening reactions and the behavior of strained heterocycles in fluorination pathways.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fluorinated fine chemicals and flavors/fragrances.

Basic Information

Product Name	7-Oxabicyclo[4.1.0]heptane, 3-(fluoromethyl)-
CAS No.	137054-12-7
Molecular Formula	C7H11FO
Molecular Weight	130.16 g/mol
Synonyms	3-(Fluoromethyl)-7-oxabicyclo[4.1.0]heptane; 3-Fluoromethyl-7-oxabicyclo[4.1.0]heptane; 1-Fluoro-2,3-epoxy-4-methylcyclopentane (related structural descriptor); Fluoromethyl oxirane fused cyclopentane; Bicyclic fluoromethyl epoxide; (1R,6S)-rel-3-(Fluoromethyl)-7-oxabicyclo[4.1.0]heptane (stereoisomer); Oxirane, [(3aR,6aS)-rel-octahydrocyclopenta[c]furanyl]methyl-, (3aR,6aS)-rel- (alternative systematic name)
EINECS	Contact for details

Quality Control

Our production of 7-Oxabicyclo[4.1.0]heptane, 3-(fluoromethyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We employ advanced analytical techniques including GC, HPLC, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment, supporting cGMP and ISO 9001 compliant workflows for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its reactive epoxide functionality and light-sensitive nature, it is recommended to store under an inert atmosphere for long-term stability and to use shortly after opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.