Description

1-Propyl-1H-Imidazole-4-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, primarily used as a key synthetic intermediate in advanced organic chemistry. Its core value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl functional group into target molecules, which is critical for modulating biological activity and physical properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs), specialty chemicals, and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially those targeting enzymes where sulfonamide groups are key pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that incorporate imidazole and sulfonamide motifs.
• Material Science Research: Employed in the development of specialty polymers, ligands for catalysis, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling, modifying, or cross-linking biomolecules in research applications.
• Custom Synthesis & Contract Manufacturing: A key reagent for fine chemical and custom synthesis houses producing high-value, low-volume specialty compounds for clients.

Basic Information

Product Name	1-Propyl-1H-Imidazole-4-Sulfonyl Chloride
CAS No.	137049-03-7
Molecular Formula	C6H9ClN2O2S
Molecular Weight	208.67 g/mol
Synonyms	1-Propylimidazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-1-propyl-1H-imidazole; 1-Propyl-1H-imidazole-4-sulfonyl chloride; 1-Propyl-1H-imidazole-4-sulfonchlorid; 1-n-Propylimidazole-4-sulfonyl chloride; 1-Propylimidazole-4-sulfonchloride; 4-(Chlorosulphonyl)-1-propylimidazole
EINECS	Contact for details

Quality Control

Our 1-Propyl-1H-Imidazole-4-Sulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.