Description

1,2-Dimethyl-1H-Imidazole-4-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative used as a key building block in organic synthesis. Its primary value lies in its role as a sulfonylation reagent, enabling the efficient introduction of the sulfonyl functional group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides that incorporate sulfonyl functional groups for enhanced activity.
• Peptide Chemistry: Employed as a sulfonylating agent for modifying amino acid side chains or protecting groups during peptide synthesis.
• Material Science: Serves as a precursor for creating functionalized polymers and advanced materials with specific surface properties.
• Chemical Biology Probes: Utilized in the development of activity-based probes and labeling reagents for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring precise sulfonylation reactions.

Basic Information

Product Name	1,2-Dimethyl-1H-Imidazole-4-Sulfonyl Chloride
CAS No.	137049-02-6
Molecular Formula	C5H7ClN2O2S
Molecular Weight	194.64 g/mol
Synonyms	1,2-Dimethylimidazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-1,2-dimethyl-1H-imidazole; 1H-Imidazole-4-sulfonyl chloride, 1,2-dimethyl-; 1,2-Dimethyl-4-imidazolesulfonyl chloride; 1,2-Dimethylimidazole-4-sulfonoyl chloride; DMISC; 1,2-Dimethyl-1H-imidazol-4-ylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 1,2-Dimethyl-1H-Imidazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.