Description

1-Methyl-1H-Imidazole-4-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, primarily used as a key synthetic intermediate in advanced organic chemistry. Its core value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl functional group into target molecules, which is crucial for modulating biological activity and physical properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs), specialty chemicals, and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of drug candidates, especially those containing sulfonamide moieties for therapeutic applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the sulfonyl group enhances efficacy.
• Material Science: Serves as a monomer or modifying agent in the creation of specialized polymers and functional materials.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for constructing complex heterocyclic scaffolds and exploring new reaction pathways.
• Dye and Pigment Industry: Employed in the synthesis of specialized dyes and colorants.
• Ligand and Catalyst Preparation: Useful for synthesizing tailored ligands for metal complexes and catalysts.

Basic Information

Product Name	1-Methyl-1H-Imidazole-4-Sulfonyl Chloride
CAS No.	137049-00-4
Molecular Formula	C4H5ClN2O2S
Molecular Weight	180.61 g/mol
Synonyms	1-Methylimidazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-1-methyl-1H-imidazole; 1-Methyl-4-imidazolesulfonyl chloride; 1-Methyl-1H-imidazole-4-sulfonyl chloride; 1-Methylimidazole-4-sulfonylchloride; N-Methylimidazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-N-methylimidazole
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Imidazole-4-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is analyzed using advanced techniques including HPLC, NMR, and titration to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.