Description

5-Chloro-1-Methyl-1H-Imidazole-4-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, enabling the efficient introduction of both the imidazole heterocycle and a sulfonamide linkage into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the imidazole-sulfonamide moiety is a key pharmacophore.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of novel polymers and functional materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of chemical probes to study biological systems.
• Dye & Pigment Manufacturing: Serves as an intermediate in the synthesis of specialized dyes and colorants.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring the construction of complex sulfonamide-containing heterocycles.

Basic Information

Product Name	5-Chloro-1-Methyl-1H-Imidazole-4-Sulfonyl Chloride
CAS No.	137048-96-5
Molecular Formula	C4H4Cl2N2O2S
Molecular Weight	239.06 g/mol
Synonyms	1-Methyl-5-chloroimidazole-4-sulfonyl chloride; 4-Chloro-1-methyl-1H-imidazole-5-sulfonyl chloride; 5-Chloro-1-methylimidazole-4-sulfonyl chloride; 1-Methyl-5-chloro-1H-imidazole-4-sulfonyl chloride; 4-Sulfonyl chloride-5-chloro-1-methylimidazole; 5-Chloro-1-methyl-1H-imidazole-4-sulfonchlorid
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-Methyl-1H-Imidazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.