Description

U-83836E is a high-purity, specialized chemical compound with significant utility in advanced research and development. This compound is valued for its role as a potent antioxidant and neuroprotective agent in preclinical studies. It is primarily sought after by pharmaceutical R&D teams and academic research institutions focused on neurology and oxidative stress pathways. The material is supplied to meet the stringent requirements of laboratory and process development applications.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of neuroprotective therapies.
• Preclinical Neuroscience Studies: Utilized in experimental models to investigate mechanisms of action against oxidative damage and neuronal cell death.
• Biochemical Assay Development: Employed as a critical reagent in high-throughput screening (HTS) assays targeting antioxidant pathways.
• Academic Research: Used in university and institutional labs for fundamental research into free radical biology and related disease mechanisms.
• Process Chemistry & Scale-up: Acts as a building block or intermediate for process optimization and the synthesis of more complex therapeutic candidates.

Basic Information

Product Name	U-83836E
CAS No.	137018-55-4
Molecular Formula	C23H32N2O3
Molecular Weight	384.52 g/mol
Synonyms	U-83836E; 21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]-pregna-1,4,9(11)-triene-3,20-dione; Lazaroid U-83836E; 21-[4-[2,6-Bis(1-pyrrolidinyl)-4-pyrimidinyl]-1-piperazinyl]pregna-1,4,9(11)-triene-3,20-dione; PNU-83836E; U 83836E
EINECS	Contact for details

Quality Control

Our U-83836E is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC and NMR. We support research and development with material that meets the exacting standards required for reliable scientific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.