Description

5-Fluoro-2-Hydroxy-3-Nitropyridine is a versatile heterocyclic building block characterized by its unique trifunctional structure, combining fluoro, hydroxy, and nitro substituents on a pyridine ring. This compound is of significant value in advanced organic synthesis, enabling the precise construction of complex molecules for research and development. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its fluorine and nitro groups for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals, organic semiconductors, and photoactive compounds.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Fine Chemical Production: Acts as a versatile intermediate for the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	5-Fluoro-2-Hydroxy-3-Nitropyridine
CAS No.	136888-20-5
Molecular Formula	C5H3FN2O3
Molecular Weight	158.09 g/mol
Synonyms	3-Nitro-5-fluoro-2-pyridinol; 5-Fluoro-3-nitro-2-pyridone; 2-Hydroxy-5-fluoro-3-nitropyridine; 5-Fluoro-2-pyridinol-3-nitro; 5-Fluoro-3-nitropyridin-2-ol; 5-Fluoro-3-nitro-2(1H)-pyridinone; 136888-20-5; 5-Fluoro-2-hydroxy-3-nitro-pyridine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Hydroxy-3-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.