Description

Tyrphostin Rg 13022 is a potent and selective tyrosine kinase inhibitor widely used in biochemical and pharmacological research. This compound is valued for its ability to modulate specific cellular signaling pathways, making it a critical tool for studying cell proliferation, differentiation, and oncogenesis. Researchers and developers in the pharmaceutical, biotechnology, and academic sectors utilize this high-purity chemical for target validation, assay development, and preclinical studies.

Application

• Biochemical Research: Used as a selective inhibitor to study EGFR (Epidermal Growth Factor Receptor) and related tyrosine kinase signaling pathways in vitro.
• Cancer Research: A key tool compound for investigating mechanisms of tumor cell growth and evaluating potential anti-cancer therapeutics.
• Cell Signaling Studies: Employed to dissect phosphorylation events and downstream effects in various cell culture models.
• Drug Discovery & Development: Serves as a reference standard and pharmacologic probe in high-throughput screening and hit validation campaigns.
• Academic & Institutional Research: Fundamental research into cellular communication, apoptosis, and metabolic regulation.

Basic Information

Product Name	Tyrphostin Rg 13022
CAS No.	136831-48-6
Molecular Formula	C16H12N2O3
Molecular Weight	280.28 g/mol
Synonyms	AG 13022; Tyrphostin AG 13022; RG 13022; (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide; RG13022; AG-13022; Benzyl (2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoate
EINECS	Contact for details

Quality Control

Our Tyrphostin Rg 13022 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.