Description

16,16-Difluoro-13,14-Dihydro-15-Carbonyl-Pge2 Benzyl Ester is a high-value, fluorinated prostaglandin E2 (PGE2) analog derivative. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting inflammation, pain, and cytoprotection. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing next-generation drug candidates and biochemical probes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel prostaglandin-based pharmaceuticals.
• Biochemical Research: Used as a reference standard or active probe in studying prostaglandin receptors (EP receptors) and their signaling pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop drugs with improved metabolic stability and potency.
• Anti-inflammatory Drug Development: Investigated for the creation of new anti-inflammatory and analgesic agents with targeted action.
• Ophthalmic Research: Potential intermediate for developing treatments for ocular conditions like glaucoma.
• Academic & Contract Research: Employed in university and CRO laboratories for fundamental research in lipid mediator biology.

Basic Information

Product Name	16,16-Difluoro-13,14-Dihydro-15-Carbonyl-Pge2 Benzyl Ester
CAS No.	136790-79-9
Molecular Formula	C29H34F2O6
Molecular Weight	516.58 g/mol
Synonyms	16,16-Difluoro-13,14-dihydro-15-keto-PGE2 benzyl ester; 15-Keto-16,16-difluoro-13,14-dihydro-PGE2 benzyl ester; Benzyl (5Z,13E)-(9S,11R,15R)-9,11,15-trihydroxy-16,16-difluoro-15-oxoprosta-5,13-dien-1-oate; Difluoroprostaglandin E2 benzyl ester derivative; 15-Oxo-16,16-difluoro-13,14-dihydro-PGE2 benzyl ester; Fluorinated PGE2 analog benzyl ester
EINECS	Contact for details

Quality Control

Our 16,16-Difluoro-13,14-Dihydro-15-Carbonyl-Pge2 Benzyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.