Description

Ramorelix is a synthetic decapeptide and a potent gonadotropin-releasing hormone (GnRH) antagonist. This compound is of significant interest in the field of endocrinology and reproductive medicine due to its ability to provide rapid and reversible suppression of gonadotropin secretion. It is primarily utilized by pharmaceutical research organizations, biotechnology companies, and academic institutions engaged in the development of novel therapeutic agents for hormone-dependent conditions.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in preclinical and clinical studies for hormone-related therapies.
• GnRH Antagonist Studies: Used as a critical tool compound in biochemical and pharmacological research to investigate the GnRH receptor pathway and its modulation.
• Reproductive Medicine: Investigated for potential applications in assisted reproductive technologies (ART) and the treatment of conditions such as endometriosis, uterine fibroids, and prostate cancer.
• Analytical Standard: Employed as a high-purity standard in quality control laboratories for method development, validation, and assay calibration using techniques like HPLC and mass spectrometry.

Basic Information

Product Name	Ramorelix
CAS No.	136639-71-9
Molecular Formula	C60H83N17O13
Molecular Weight	1230.4 g/mol
Synonyms	Ac-D-2-Nal-D-4-Cpa-D-3-Pal-Ser-Tyr-D-Hci-Leu-Lys(iPr)-Pro-D-Ala-NH2; Ramorelix Acetate; FE 200486; GnRH Antagonist (FE 200486); [Ac-D-2-Nal1, D-4-Cpa2, D-3-Pal3, Ser4, Tyr5, D-Hci6, Leu7, Lys(iPr)8, Pro9, D-Ala10]-GnRH
EINECS	Contact for details

Quality Control

Our Ramorelix is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by IR and HPLC, purity assay, and determination of related substances and residual solvents, to ensure it meets the stringent requirements for research-grade peptides. Certificates of Analysis (COA) documenting full specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.