Description

2,4-Difluoro-6-Hydroxybenzaldehyde is a specialized fluorinated aromatic aldehyde building block of significant synthetic utility. Its molecular structure, featuring both aldehyde and phenolic hydroxyl groups on a difluorinated benzene ring, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Precursor: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable scaffold in academic and industrial R&D for exploring new chemical entities and structure-activity relationships (SAR).
• Fluorine Chemistry Studies: Used as a model compound in methodological development for introducing and manipulating fluorine-containing functional groups.

Basic Information

Product Name	2,4-Difluoro-6-Hydroxybenzaldehyde
CAS No.	136516-64-8
Molecular Formula	C7H4F2O2
Molecular Weight	158.10 g/mol
Synonyms	6-Hydroxy-2,4-difluorobenzaldehyde; 2,4-Difluoro-6-hydroxybenzaldehyde; 2,4-Difluoro-6-formylphenol; 2,4-Difluoro-6-hydroxy-benzaldehyde; 2,4-Difluoro-6-hydroxybenzenecarboxaldehyde; 2,4-Difluoro-6-hydroxybenzene-1-carbaldehyde; 2,4-Difluoro-6-hydroxybenzaldehyde (6-Hydroxy-2,4-difluorobenzaldehyde)
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-6-Hydroxybenzaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For customers with specific regulatory needs, we can discuss compliance with relevant frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.