Description

2,6-Difluoropyridine-3-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex, fluorinated heterocyclic systems via cross-coupling reactions like the Suzuki-Miyaura reaction. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used to create novel fluorinated pyridine-based herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Serves as a building block for developing advanced organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to synthesize fluorinated molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring the introduction of a difluoropyridine moiety.

Basic Information

Product Name	2,6-Difluoropyridine-3-Boronic Acid
CAS No.	136466-94-9
Molecular Formula	C5H4BF2NO2
Molecular Weight	158.90 g/mol
Synonyms	(3-Borono-2,6-difluoropyridine); 2,6-Difluoropyridine-3-boronic acid; 2,6-Difluoro-3-pyridineboronic acid; 3-Borono-2,6-difluoropyridine; (2,6-Difluoropyridin-3-yl)boronic acid; 2,6-Difluoro-3-pyridinylboronic acid; Boronic acid, B-(2,6-difluoro-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 2,6-Difluoropyridine-3-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to support cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.