Description

Noradrenaline Transporter is a high-purity chemical reference standard, identified by CAS NO 136253-20-8, that plays a critical role in neuroscience research and pharmaceutical development. Its primary value lies in its use as a selective ligand for studying the norepinephrine transporter (NET), a key protein target for modulating neurotransmitter reuptake. This compound is essential for researchers and developers in the pharmaceutical, biotechnology, and academic sectors focused on neuropharmacology, psychiatric disorders, and cardiovascular research.

Application

• Neuroscience Research: Used as a selective ligand in binding assays and autoradiography to study the distribution and function of the norepinephrine transporter (NET).
• Drug Discovery & Development: Serves as a critical reference standard in high-throughput screening (HTS) campaigns to identify novel antidepressants, stimulants, or agents for attention-deficit hyperactivity disorder (ADHD).
• Biochemical Assays: Employed in in vitro studies to investigate transporter kinetics, inhibitor potency, and structure-activity relationships (SAR).
• Pharmacological Profiling: Essential for characterizing the selectivity and mechanism of action of new chemical entities targeting monoamine transporters.
• Diagnostic Tool Development: Potential use in the development of radiolabeled probes for positron emission tomography (PET) imaging of NET density in the brain.
• Academic & Institutional Research: Supports fundamental research into catecholamine systems, stress response, mood regulation, and autonomic nervous system function.

Basic Information

Product Name	Noradrenaline Transporter
CAS No.	136253-20-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NET Ligand; Norepinephrine Transporter Ligand; Noradrenaline Transporter Inhibitor; (1R,2S)-3-(3,4-Dichlorophenoxy)-1,2,3,4-tetrahydro-1-naphthalenamine; Nisoxetine analog; Research Compound 136253-20-8
EINECS	Contact for details

Quality Control

Our Noradrenaline Transporter is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.