Description

Glucoallosamidin A is a potent and specific inhibitor of the enzyme N-acetyl-β-D-glucosaminidase (NAGase). This compound is a critical research tool for studying carbohydrate metabolism, glycoprotein processing, and lysosomal storage disorders. It is primarily utilized by biochemists, pharmaceutical researchers, and academic institutions engaged in enzymology and glycoscience research. The high specificity of Glucoallosamidin A makes it invaluable for mechanistic studies and inhibitor screening programs.

Application

• Enzymology Research: As a specific inhibitor for studying the function and kinetics of N-acetyl-β-D-glucosaminidase (NAGase).
• Glycobiology Studies: For investigating pathways of glycoprotein and glycolipid degradation within lysosomes.
• Disease Model Research: Used in cellular and biochemical models of lysosomal storage diseases, such as Tay-Sachs and Sandhoff disease.
• Pharmaceutical Development: Serves as a reference compound or lead structure in drug discovery programs targeting glycosidase enzymes.
• Diagnostic Tool Development: Potential use in the development of assays to measure NAGase activity in clinical or research settings.
• Biochemical Reagent: Employed as a high-purity biochemical standard in laboratory experiments.

Basic Information

Product Name	Glucoallosamidin A
CAS No.	136236-41-4
Molecular Formula	C14H26N2O9
Molecular Weight	366.37 g/mol
Synonyms	Allosamidin, Glucoallosamidin; N,N'-Diacetyl-β-D-glucosaminyl-(1→4)-2-amino-2-deoxy-β-D-glucopyranose; (2R,3R,4S,5R,6R)-2-[[(2R,3R,4R,5S,6R)-3-Acetamido-5-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol; NAGase Inhibitor; N-Acetyl-β-D-glucosaminidase Inhibitor
EINECS	Contact for details

Quality Control

Our Glucoallosamidin A is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for fine chemical and biochemical reagent production to support reliable and reproducible scientific results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Biological Activity (NAGase Inhibition)	Conforms to expected IC50 range

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.