Description

Protein Kinase Inhibitor M (6-24) is a synthetic peptide inhibitor designed to selectively target specific protein kinase activity. This compound is a critical research tool for elucidating signal transduction pathways and studying cellular processes like proliferation and apoptosis. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in drug discovery and biochemical research.

Application

• Biochemical Research: A key reagent for studying kinase-mediated signaling cascades in vitro.
• Drug Discovery & Screening: Used as a reference standard or tool compound in high-throughput screening assays to identify novel therapeutic agents.
• Cell Biology Studies: Employed to inhibit specific kinase activity to understand its role in cell cycle regulation, differentiation, and programmed cell death.
• Target Validation: Serves as a pharmacological tool to validate protein kinases as potential drug targets in disease models.
• Enzyme Kinetics: Used in experiments to determine enzyme inhibition constants (IC50/Ki) and mechanism of action studies.

Basic Information

Product Name	Protein Kinase Inhibitor M (6-24)
CAS No.	136058-51-0
Molecular Formula	C99H155N29O21
Molecular Weight	2099.5 g/mol
Synonyms	PKI(6-24) amide; Protein Kinase Inhibitor Peptide (6-24); cAMP-dependent Protein Kinase Inhibitor (6-24); PKI Peptide (6-24); TTYADFIASGRTGRRNAI-NH2; H-Tyr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2; PKA Inhibitor (6-24)
EINECS	Contact for details

Quality Control

Our Protein Kinase Inhibitor M (6-24) is manufactured under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to ISO 9001 quality management principles, and our analytical methods comply with standard pharmacopeial practices for peptide characterization.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 8.0%
Acetate Content (HPIC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.