Description

3',4'-Difluorobiphenyl-4-Carbaldehyde is a high-purity, multi-functional aromatic aldehyde building block. This compound is valued for its role as a critical intermediate in the synthesis of advanced organic materials and active pharmaceutical ingredients (APIs). It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel fluorinated compounds with specific electronic and steric properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the difluorobiphenyl moiety can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated mesogens and electron-transport materials in display and lighting technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, solubility, and optical properties.
• Organic Synthesis & Research: A versatile reagent for Suzuki-Miyaura cross-coupling and other palladium-catalyzed reactions to create complex biphenyl structures.

Basic Information

Product Name	3',4'-Difluorobiphenyl-4-Carbaldehyde
CAS No.	135862-45-2
Molecular Formula	C13H8F2O
Molecular Weight	218.20 g/mol
Synonyms	4-(3,4-Difluorophenyl)benzaldehyde; 4-Formyl-3',4'-difluorobiphenyl; 3,4-Difluoro-4'-formylbiphenyl; 4-Biphenylcarboxaldehyde, 3',4'-difluoro-; (3,4-Difluorophenyl)benzaldehyde; 4-(3,4-Difluorophenyl)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3',4'-Difluorobiphenyl-4-Carbaldehyde is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We guarantee high chemical purity and lot-to-lot consistency to meet the stringent requirements of research and commercial synthesis. A detailed Certificate of Analysis (COA) with specifications for identity, purity, and impurities is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.