Description

2-(3-(4-Hydroxy-3-Iodophenyl)Propionamido)-n-Ethyl-7-(Aminocarbonyl)-7-Desacetylforskolin is a chemically modified derivative of forskolin, a well-known diterpene activator of adenylate cyclase. This compound is specifically engineered for advanced biochemical and pharmacological research, offering a targeted tool for modulating cyclic AMP (cAMP) signaling pathways. It is primarily utilized by researchers in pharmaceutical development, biotechnology, and academic institutions for investigating cellular signaling, enzyme activity, and as a reference standard.

Application

• Biochemical Research: As a key tool compound for studying adenylate cyclase activation and intracellular cAMP elevation in cell-based assays.
• Pharmaceutical R&D: Serving as a critical intermediate or reference standard in the development of novel therapeutics targeting metabolic and cardiovascular diseases.
• Signal Transduction Studies: Used to investigate G-protein-coupled receptor (GPCR) pathways and downstream effects in various cell types.
• Enzyme Inhibition/Activation Assays: Employed in high-throughput screening (HTS) to identify modulators of related enzymatic activity.
• Academic Research: Utilized in university and institutional labs for fundamental research in molecular biology and physiology.
• Reference Standard: For quality control and analytical method development (HPLC, LC-MS) in pharmaceutical and contract research organizations (CROs).

Basic Information

Item	Detail
Product Name	2-(3-(4-Hydroxy-3-Iodophenyl)Propionamido)-n-Ethyl-7-(Aminocarbonyl)-7-Desacetylforskolin
CAS No.	135159-45-4
Molecular Formula	C27H31IN2O6
Molecular Weight	606.46 g/mol
Synonyms	7-Desacetyl-7-[(aminoacetyl)amino]forskolin derivative; 7-Carbamoyl-7-desacetylforskolin derivative; Iodinated forskolin analog; 2-[3-(4-Hydroxy-3-iodophenyl)propanamido]-N-ethyl-7-carbamoyl-7-desacetylforskolin; cAMP pathway activator derivative; Forskolin-7-carboxamide analog; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Each batch is characterized using advanced analytical techniques to confirm identity and purity. Certificates of Analysis (COA) detailing purity, analytical methods (HPLC, NMR), and results are available upon request. We adhere to a quality management system suitable for supplying reference standards and high-purity biochemical tools.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.