Description

Maduropeptin A1 is a potent enediyne antibiotic isolated from *Actinomadura madurae* with significant biological activity. This compound is of high interest for its unique mechanism of action, which involves DNA cleavage, making it a valuable tool in biochemical research and a lead structure for novel therapeutic development. It is primarily utilized by researchers in pharmaceutical R&D, oncology, and molecular biology for studying DNA-protein interactions and developing new anticancer agents.

Application

• Biochemical Research: Used as a molecular probe to study DNA damage, repair mechanisms, and the function of enediyne antibiotics.
• Anticancer Agent Development: Serves as a critical lead compound in the research and development of novel chemotherapeutic drugs targeting tumor DNA.
• Microbiology Studies: Employed in studies of antibiotic resistance and the discovery of new bioactive compounds from actinomycetes.
• Pharmaceutical R&D: Utilized in high-throughput screening and mechanism-of-action studies for new drug candidates.
• Academic Research: A key reagent in university and institutional labs focusing on natural product chemistry, chemical biology, and medicinal chemistry.

Basic Information

Product Name	Maduropeptin A1
CAS No.	134910-70-6
Molecular Formula	C59H89N5O21S
Molecular Weight	1244.42 g/mol
Synonyms	Maduropeptin A1; Maduropeptin; Antibiotic C 1027 chromophore; C-1027 Chromophore; Enediyne antibiotic C1027; 9,10-Dehydro-5,8,11,14-tetrahydroxy-3-[[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-2-oxanyl]oxy]oxan-2-yl]oxy]-2-methyl-1,4,5,8-tetrahydroanthracene-6,12-dione
EINECS	Contact for details

Quality Control

Our Maduropeptin A1 is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and potency. We adhere to relevant standards for research-grade biochemicals to support reliable and reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain integrity. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	Yellow to brownish powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Biological Activity	Assayed; data on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.