Description

Sarcosine, [Glycine 1-14C] CAS NO 134767-26-3 is a carbon-14 labeled derivative of the amino acid sarcosine (N-methylglycine), a key compound in biological and metabolic research. This isotopically labeled product is essential for precise tracer studies, enabling researchers to track metabolic pathways, study protein synthesis, and investigate biochemical mechanisms with high sensitivity. It is a critical reagent for pharmaceutical R&D, academic research, and diagnostic development in the life sciences sector.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer in studies of glycine and sarcosine metabolism, one-carbon cycle, and related biochemical pathways.
• Drug Metabolism and Pharmacokinetics (DMPK): Essential for ADME (Absorption, Distribution, Metabolism, Excretion) studies to track the fate of new drug candidates in biological systems.
• Biomedical Research: Facilitates research into diseases where glycine/sarcosine metabolism is implicated, such as certain cancers and neurological disorders.
• Proteomics and Protein Synthesis Studies: Enables the investigation of protein turnover, synthesis rates, and post-translational modification dynamics.
• Diagnostic Agent Development: Serves as a precursor in the development of novel radiolabeled diagnostic probes for imaging techniques like PET (Positron Emission Tomography), when combined with appropriate isotopes.
• Environmental and Agricultural Science: Applied in studies of nutrient cycling, plant metabolism, and environmental fate of nitrogen-containing compounds.

Basic Information

Product Name	Sarcosine, [Glycine 1-14C]
CAS No.	134767-26-3
Molecular Formula	C14CH5NO2 or C2H514CNO2
Molecular Weight	~91.08 g/mol (exact mass depends on 14C enrichment)
Synonyms	(2-14C)Sarcosine; N-Methyl[1-14C]glycine; [1-14C]Sarcosine; (Carboxy-14C)Sarcosine; N-Methylamino[1-14C]acetic Acid; [Glycine-1-14C]Sarcosine; 2-(Methylamino)acetic-1-14C acid
EINECS	Contact for details

Quality Control

Every batch of Sarcosine, [Glycine 1-14C] is manufactured and analyzed under strict quality systems to ensure high chemical and radiochemical purity, specific activity, and stability. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, radiochemical concentration, and specific activity are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) to maintain stability. This material is hygroscopic (moisture-sensitive); ensure containers are sealed properly after each use to prevent degradation from atmospheric moisture. Follow all applicable radiation safety and handling protocols for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solvent (if supplied in solution)	Specified on COA (e.g., Water, Ethanol)
Concentration	Specified on COA (e.g., 1.0 mCi/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.