Description

5(6)-(Biotinamidocaproylamido) Pentylthi is a specialized biotin derivative featuring a reactive thiol group and a long-chain linker. This compound is critical for creating stable, site-specific biotin conjugations, enabling high-affinity capture and detection in advanced biochemical assays. It is an essential reagent for researchers and manufacturers in the pharmaceutical, diagnostics, and life science research sectors who require precise labeling and purification of biomolecules.

Application

• Bioconjugation & Protein Labeling: Site-specific attachment of biotin tags to proteins, antibodies, and peptides via thiol-reactive chemistry for downstream purification or detection.
• Affinity Chromatography Ligand Synthesis: Immobilization onto solid supports (e.g., agarose, magnetic beads) to create custom streptavidin/avidin affinity columns.
• Diagnostic Assay Development: Production of biotinylated probes and detection reagents for ELISA, lateral flow assays, and other immunoassay platforms.
• Cell Surface Labeling: Biotinylation of cell surface thiol groups for isolation, tracking, or analysis of specific cell populations.
• Drug Delivery & Targeting: Conjugation to therapeutic agents or nanoparticles to create targeted delivery systems utilizing the biotin-streptavidin interaction.
• Microarray & Biosensor Fabrication: Functionalization of sensor surfaces with biotin to capture streptavidin-linked analytes.

Basic Information

Product Name	5(6)-(Biotinamidocaproylamido) Pentylthi
CAS No.	134759-22-1
Molecular Formula	C22H40N4O3S2
Molecular Weight	472.70 g/mol
Synonyms	Biotin-PEAC5-Maleimide; Biotinamidocaproylamido Pentylthi; Biotin-PEAC5-Mal; N-(5-Maleimidopentyl)biotinamide; 1-Biotinamido-4-(4-(maleimidomethyl)cyclohexanecarboxamido)butane; Biotin Maleimide (long chain); Biotin-C5-Maleimide; Biotinylated Maleimide (C5 linker)
EINECS	Contact for details

Quality Control

Our 5(6)-(Biotinamidocaproylamido) Pentylthi is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for sensitive research and diagnostic applications. Certificates of Analysis (COA) with full specification data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.