Description

Reveromycin A CAS NO 134615-37-5 is a specialized spiroketal polyketide compound belonging to the reveromycin class of antibiotics. This compound is valued for its potent and selective biological activity, particularly as an inhibitor of eukaryotic protein synthesis and for inducing apoptosis in specific cell types. It serves as a critical research tool and building block for scientists in pharmaceutical development and life sciences research, enabling the study of cellular mechanisms and the discovery of novel therapeutic agents.

Application

• Biomedical Research: Used as a selective cytotoxin in studies of osteoclast biology and bone resorption mechanisms.
• Anticancer Agent Development: Investigated for its apoptosis-inducing properties in various cancer cell lines, serving as a lead compound for novel oncology therapeutics.
• Antifungal Research: Explored for its activity against pathogenic fungi, contributing to the development of new antifungal agents.
• Chemical Biology Tool: Employed to study protein synthesis inhibition and specific intracellular signaling pathways.
• Pharmaceutical Intermediate: Acts as a key chiral synthon or precursor in the complex synthesis of other bioactive molecules.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in microbiology, cell biology, and medicinal chemistry.

Basic Information

Product Name	Reveromycin A
CAS No.	134615-37-5
Molecular Formula	C₃₇H₅₈O₁₂
Molecular Weight	694.86 g/mol
Synonyms	Reveromycin A; Antibiotic Reveromycin A; Reveromycin; (3S,4R,5S,6R,8R,10R,11S,12S,13R,14S,16R,18R,19S,20R,22S,23R,24S,25S,26R,27S,28R)-27-[(2S,3S,4S,5R)-3,4-Dihydroxy-5-methyl-6-oxooxan-2-yl]oxy-4,5,11,13,14,16,18,20,22,24,26-undecahydroxy-3,6,8,10,12,15,19,23,25-nonamethyl-1-oxacyclooctacosane-2,17-dione; Antibiotic XK 90-1; XK 90-1
EINECS	Contact for details

Quality Control

Every batch of Reveromycin A is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.