Description

Seocalcitol CAS NO 134404-52-7 is a synthetic vitamin D3 analog, specifically a 19-nor derivative, designed for targeted biological activity. This compound is of significant interest in pharmaceutical research and development due to its potent and selective action on vitamin D receptors. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics for conditions such as psoriasis, cancer, and secondary hyperparathyroidism.

Application

• Pharmaceutical R&D for novel vitamin D receptor (VDR) agonists.
• Preclinical and clinical studies targeting hyperproliferative skin disorders like psoriasis.
• Investigation of therapeutic agents for various cancers, including prostate and breast cancer.
• Research into treatments for secondary hyperparathyroidism associated with chronic kidney disease.
• Biochemical research as a tool compound to study VDR signaling pathways.
• Development of topical formulations for dermatological applications.

Basic Information

Product Name	Seocalcitol
CAS No.	134404-52-7
Molecular Formula	C₂₇H₄₄O₃
Molecular Weight	416.64 g/mol
Synonyms	EB 1089; 19-nor-1α,25-Dihydroxyvitamin D3; 1α,25-Dihydroxy-19-norvitamin D3; 1α,25-Dihydroxy-19-nor-cholecalciferol; Seocalcitolum; Leo 210116; 19-Nor-1,25-dihydroxyvitamin D3
EINECS	Contact for details

Quality Control

Our Seocalcitol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.