Description

Mannostatin A, Hydrochloride is a potent and specific inhibitor of α-mannosidase enzymes, a key compound for glycobiology research. Its primary value lies in its ability to disrupt N-linked glycan processing, making it an essential tool for studying glycosylation pathways and their roles in cellular function and disease. This product is critical for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors, particularly those focused on metabolic disorders, cancer research, and the development of glycosidase-targeted therapeutics.

Application

• Glycobiology Research: A fundamental tool for investigating the structure, biosynthesis, and function of N-linked glycans in cellular systems.
• Enzyme Inhibition Studies: Used to specifically inhibit Golgi α-mannosidase I and II, facilitating studies on enzyme kinetics and mechanism of action.
• Pharmaceutical R&D: Serves as a lead compound or reference standard in the discovery of novel therapeutics targeting glycosylation-related diseases, including certain cancers and lysosomal storage disorders.
• Cell Biology & Signaling: Employed to study the role of protein glycosylation in cell adhesion, signaling, and immune response modulation.
• Biochemical Assay Development: Used as a control or standard in high-throughput screening assays designed to identify new glycosidase inhibitors.
• Academic Research: Essential for university and institutional labs conducting basic research in biochemistry, molecular biology, and chemical biology.

Basic Information

Product Name	Mannostatin A, Hydrochloride
CAS No.	134235-13-5
Molecular Formula	C7H14N2O4 • HCl
Molecular Weight	226.66 g/mol (free base: 190.20)
Synonyms	Mannostatin A HCl; (2R,3R,4R,5S)-1,5-Dideoxy-1,5-imino-3,4-O-isopropylidene-D-mannitol Hydrochloride; 3,4-O-Isopropylidene-1,5-dideoxy-1,5-imino-D-mannitol Hydrochloride; α-Mannosidase Inhibitor; Golgi α-Mannosidase II Inhibitor; Swainsonine analog; Imino sugar derivative
EINECS	Contact for details

Quality Control

Our Mannostatin A, Hydrochloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material suitable for use as a reference standard upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant for long-term storage to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.