Description

15-Propionat-Prostaglandin F2Alpha-Isopropyl Ester is a synthetic prostaglandin analog, a key intermediate in the development of advanced pharmaceutical compounds. This high-purity intermediate is critical for ensuring the efficacy and consistency of final active pharmaceutical ingredients (APIs) in therapeutic applications. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers specializing in ophthalmic, cardiovascular, and reproductive health products.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of prostaglandin-based APIs for glaucoma treatment (e.g., Latanoprost analogs).
• Ophthalmic Drug Development: Used in research and production of drugs that reduce intraocular pressure.
• Biochemical Research: Acts as a standard or reagent in studies involving prostaglandin receptors and signaling pathways.
• Veterinary Pharmaceuticals: Employed in the formulation of therapeutics for animal reproduction and fertility management.
• Fine Chemical Synthesis: A versatile synthon for creating novel prostaglandin derivatives with tailored biological activity.

Basic Information

Product Name	15-Propionat-Prostaglandin F2Alpha-Isopropyl Ester
CAS No.	134152-12-8
Molecular Formula	C26H42O6
Molecular Weight	450.61 g/mol
Synonyms	15(R)-15-Methyl Prostaglandin F2α Isopropyl Ester; 15-Methyl PGF2α Isopropyl Ester; Isopropyl (5Z,9α,11α,13E,15R)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oate; 15-Methyl Prostaglandin F2α Isopropyl Ester; Prostaglandin F2α 15-Methyl Isopropyl Ester; 15-Me-PGF2α Isopropyl Ester; PGF2α Analog Intermediate; Travoprost Related Compound
EINECS	Contact for details

Quality Control

Our 15-Propionat-Prostaglandin F2Alpha-Isopropyl Ester is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.