Description

2,5-Difluoro-4-(Trifluoromethyl)Benzaldehyde is a high-value fluorinated aromatic aldehyde building block. This compound is essential for introducing the 2,5-difluoro-4-(trifluoromethyl)benzyl moiety into complex molecules, significantly altering their electronic properties, lipophilicity, and metabolic stability. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving performance and durability.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique thermal, chemical, and surface properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for developing new fluorination methodologies and catalytic processes.
• Material Science: Used in the synthesis of advanced coatings, sensors, and porous framework materials due to its specific steric and electronic profile.

Basic Information

Product Name	2,5-Difluoro-4-(Trifluoromethyl)Benzaldehyde
CAS No.	134099-33-5
Molecular Formula	C8H3F5O
Molecular Weight	210.10 g/mol
Synonyms	4-(Trifluoromethyl)-2,5-difluorobenzaldehyde; 2,5-Difluoro-α,α,α-trifluoro-p-tolualdehyde; Benzaldehyde, 2,5-difluoro-4-(trifluoromethyl)-; 2,5-Difluoro-4-trifluoromethylbenzaldehyde; 2,5-Difluoro-α,α,α-trifluoro-4-tolualdehyde; 4-(Trifluoromethyl)-2,5-difluorobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for precise characterization. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request. Our quality management system supports cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.