Description

4,5-Difluoro-2-(Trifluoromethyl)Benz Aldehyde is a high-value, multi-fluorinated aromatic aldehyde building block. This compound matters for its unique trifluoromethyl and difluoro substitution pattern, which imparts significant lipophilicity, metabolic stability, and electronic properties to target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of advanced intermediates in drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving performance and stability.
• Advanced Polymer Chemistry: Incorporated as a monomer or cross-linking agent to produce specialty polymers with enhanced chemical and thermal resistance.
• Organic Synthesis & Catalysis: Acts as a versatile electrophile in cross-coupling reactions, nucleophilic additions, and as a ligand precursor in organometallic chemistry.
• Material Science Research: Employed in the development of novel fluorinated coatings, surfactants, and specialty chemicals with unique surface properties.

Basic Information

Item	Detail
Product Name	4,5-Difluoro-2-(Trifluoromethyl)Benz Aldehyde
CAS No.	134099-22-2
Molecular Formula	C8H3F5O
Molecular Weight	210.10 g/mol
Synonyms	2-(Trifluoromethyl)-4,5-difluorobenzaldehyde; 4,5-Difluoro-2-trifluoromethylbenzaldehyde; 4,5-Difluoro-α,α,α-trifluoro-o-tolualdehyde; 2-(Trifluoromethyl)-4,5-difluorobenzenecarboxaldehyde; 4,5-Difluoro-2-(trifluoromethyl)benzenecarbaldehyde; 1,2-Difluoro-4-formyl-5-(trifluoromethyl)benzene; Aldehyde C8H3F5O (related to CAS 134099-22-2)
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-2-(Trifluoromethyl)Benz Aldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.