Description

tert-Butyl 2-(Chlorosulfonyl)Ethylcarbamate is a high-value, reactive chemical intermediate featuring both a carbamate protecting group and a chlorosulfonyl moiety. This dual functionality makes it a critical building block for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the introduction of sulfonamide or sulfonylurea groups in drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides that require sulfonyl-based bioactive cores.
• Peptide Modification: Serves as a reagent for the selective modification of amino acid side chains, such as lysine, to introduce sulfonamide linkages.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with sulfonyl chloride functionality.
• Chemical Biology Probes: Utilized in the synthesis of activity-based probes (ABPs) for studying enzyme function and inhibition.
• Library Synthesis: A versatile building block for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	tert-Butyl 2-(Chlorosulfonyl)Ethylcarbamate
CAS No.	134019-73-1
Molecular Formula	C7H14ClNO4S
Molecular Weight	243.71 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]ethanesulfonyl chloride; N-Boc-2-aminoethanesulfonyl chloride; tert-Butyl N-(2-chlorosulfonylethyl)carbamate; Boc-β-alanine sulfonyl chloride analog; 2-(Boc-amino)ethanesulfonyl chloride; (2-{[(tert-Butoxy)carbonyl]amino}ethyl)sulfonyl chloride; N-(tert-Butoxycarbonyl)-2-aminoethanesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 2-(Chlorosulfonyl)Ethylcarbamate is produced and tested under strict quality management systems. We ensure high purity and consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee reliable performance in your synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C (refrigerated) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.